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Volume 43, Issue 6

In this issue
Research Highlights
Original Articles
In Memoriam
Also new
Have you visited the Neuropsychopharmacology Archival Perspectives page? 

Highlighting the most cited articles from previous NPP issues. Recent additions include:

- Abnormal fear conditioning and amygdala processing in an animal model of autism
- Neural mechanisms of extinction learning and retrieval
- Neurobiological similarities in depression and drug dependence

Click here to access over 50 NPP articles from the past 5 years >>> 


The Relationship Between Dopamine Synthesis Capacity and Release: Implications for Psychosis

Matthew M Nour, Robert McCutcheon & Oliver D Howes

Neuropsychopharmacology 2018 43 :1195 - 1196; April 19, 2018; 10.1038/npp.2017.293


Abstract | Full Text

Research Highlights

Reversing Cocaine-Induced Adaptations and Reducing Relapse: An Opportunity for Repurposing Riluzole

Joseph J Ziminski & Eisuke Koya

Neuropsychopharmacology 2018 43 :1197 - 1198; January 17, 2018; 10.1038/npp.2017.300


Abstract | Full Text

A Role for Prefrontal Cortical NMDA Receptors in Murine Alcohol-Heightened Aggression

Mary M Torregrossa

Neuropsychopharmacology 2018 43 :1199 - 1200; January 10, 2018; 10.1038/npp.2017.286


Abstract | Full Text

Original Articles

Dopamine Synthesis Capacity is Associated with D2/3 Receptor Binding but Not Dopamine Release

Anne S Berry, Vyoma D Shah, Daniella J Furman, Robert L White III, Suzanne L Baker et al.

Neuropsychopharmacology 2017 43 :1201 - 1211; August 17, 2017; 10.1038/npp.2017.180


Abstract | Full Text

Riluzole Impairs Cocaine Reinstatement and Restores Adaptations in Intrinsic Excitability and GLT-1 Expression

Marian T Sepulveda-Orengo, Kati L Healey, Ronald Kim, Alyson C Auriemma, Jennifer Rojas et al.

Neuropsychopharmacology 2017 43 :1212 - 1223; October 09, 2017; 10.1038/npp.2017.244


Abstract | Full Text

A Role for Prefrontal Cortical NMDA Receptors in Murine Alcohol-Heightened Aggression

Emily L Newman, Miho Terunuma, Tiffany L Wang, Nishani Hewage, Matthew B Bicakci et al.

Neuropsychopharmacology 2017 43 :1224 - 1234; October 20, 2017; 10.1038/npp.2017.253


Abstract | Full Text

Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans

Anita C Hansson, Anne Koopmann, Stefanie Uhrig, Sina Bühler, Esi Domi et al.

Neuropsychopharmacology 2017 43 :1235 - 1246; November 01, 2017; 10.1038/npp.2017.257


Abstract | Full Text

Dopaminergic Genetic Variation Influences Aripiprazole Effects on Alcohol Self-Administration and the Neural Response to Alcohol Cues in a Randomized Trial

Joseph P Schacht, Konstantin E Voronin, Patrick K Randall & Raymond F Anton

Neuropsychopharmacology 2017 43 :1247 - 1256; December 06, 2017; 10.1038/npp.2017.298


Abstract | Full Text

Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice

Laura B Ferguson, Angela R Ozburn, Igor Ponomarev, Pamela Metten, Matthew Reilly et al.

Neuropsychopharmacology 2017 43 :1257 - 1266; December 18, 2017; 10.1038/npp.2017.301


Abstract | Full Text

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors

Alan S Lewis, Steven T Pittenger, Yann S Mineur, Dawson Stout, Philip H Smith et al.

Neuropsychopharmacology 2017 43 :1267 - 1275; November 07, 2017; 10.1038/npp.2017.276


Abstract | Full Text

A Novel Method for Chronic Social Defeat Stress in Female Mice

Alexander Z Harris, Piray Atsak, Zachary H Bretton, Emma S Holt, Raisa Alam et al.

Neuropsychopharmacology 2017 43 :1276 - 1283; November 01, 2017; 10.1038/npp.2017.259


Abstract | Full Text

Enhancing Endocannabinoid Neurotransmission Augments The Efficacy of Extinction Training and Ameliorates Traumatic Stress-Induced Behavioral Alterations in Rats

Maria Morena, Andrea Berardi, Paola Colucci, Maura Palmery, Viviana Trezza et al.

Neuropsychopharmacology 2017 43 :1284 - 1296; December 21, 2017; 10.1038/npp.2017.305


Abstract | Full Text

Generalization of Conditioned Auditory Fear is Regulated by Maternal Effects on Ventral Hippocampal Synaptic Plasticity

Huy-Binh Nguyen, Carine Parent, Yiu Chung Tse, Tak Pan Wong & Michael J Meaney

Neuropsychopharmacology 2017 43 :1297 - 1307; November 20, 2017; 10.1038/npp.2017.281


Abstract | Full Text

Association of Serotonin Transporter Gene AluJb Methylation with Major Depression, Amygdala Responsiveness, 5-HTTLPR/rs25531 Polymorphism, and Stress

Ilona Schneider, Harald Kugel, Ronny Redlich, Dominik Grotegerd, Christian Bürger et al.

Neuropsychopharmacology 2017 43 :1308 - 1316; November 07, 2017; 10.1038/npp.2017.273


Abstract | Full Text

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Tocilizumab, An Interleukin-6 Receptor Antibody, For Residual Symptoms in Schizophrenia

Ragy R Girgis, Adam Ciarleglio, Tse Choo, Gregory Haynes, Joan M Bathon et al.

Neuropsychopharmacology 2017 43 :1317 - 1323; November 01, 2017; 10.1038/npp.2017.258


Abstract | Full Text

S-Ketamine-Induced NMDA Receptor Blockade during Natural Speech Production and Its Implications for Formal Thought Disorder in Schizophrenia: A Pharmaco-fMRI Study

Arne Nagels, Maurice Cabanis, Andrea Oppel, Andre Kirner-Veselinovic, Christian Schales et al.

Neuropsychopharmacology 2017 43 :1324 - 1333; November 06, 2017; 10.1038/npp.2017.270


Abstract | Full Text

Initial Cross-Over Test of A Positive Allosteric Modulator of Alpha-7 Nicotinic Receptors to Aid Cessation in Smokers With Or Without Schizophrenia

Kenneth A Perkins, K N Roy Chengappa, Joshua L Karelitz, Margaret C Boldry, Valerie Michael et al.

Neuropsychopharmacology 2017 43 :1334 - 1342; November 29, 2017; 10.1038/npp.2017.292


Abstract | Full Text

Neuregulin 3 Signaling Mediates Nicotine-Dependent Synaptic Plasticity in the Orbitofrontal Cortex and Cognition

Luyi Zhou, Miranda L Fisher, Robert D Cole, Thomas J Gould, Vinay Parikh et al.

Neuropsychopharmacology 2017 43 :1343 - 1354; November 07, 2017; 10.1038/npp.2017.278


Abstract | Full Text

Error-related Brain Activity as a Treatment Moderator and Index of Symptom Change during Cognitive-Behavioral Therapy or Selective Serotonin Reuptake Inhibitors

Stephanie M Gorka, Katie L Burkhouse, Heide Klumpp, Amy E Kennedy, Kaveh Afshar et al.

Neuropsychopharmacology 2017 43 :1355 - 1363; November 28, 2017; 10.1038/npp.2017.289


Abstract | Full Text

Is Neural Processing of Negative Stimuli Altered in Addiction Independent of Drug Effects? Findings From Drug-Naïve Youth with Internet Gaming Disorder

Sarah W Yip, James J Gross, Megha Chawla, Shan-Shan Ma, Xing-Hui Shi et al.

Neuropsychopharmacology 2017 43 :1364 - 1372; November 20, 2017; 10.1038/npp.2017.283


Abstract | Full Text

Role of Glutamatergic Projections from the Ventral CA1 to Infralimbic Cortex in Context-Induced Reinstatement of Heroin Seeking

Na Wang, Feifei Ge, Cailian Cui, Yijing Li, Xiaowei Sun et al.

Neuropsychopharmacology 2017 43 :1373 - 1384; November 14, 2017; 10.1038/npp.2017.279


Abstract | Full Text

A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin

Jennifer A Martin, Aaron Caccamise, Craig T Werner, Rathipriya Viswanathan, Jessie J Polanco et al.

Neuropsychopharmacology 2017 43 :1385 - 1394; December 20, 2017; 10.1038/npp.2017.303


Abstract | Full Text

A-Kinase Anchoring Protein 150 (AKAP150) Promotes Cocaine Reinstatement by Increasing AMPA Receptor Transmission in the Accumbens Shell

Leonardo A Guercio, Mackenzie E Hofmann, Sarah E Swinford-Jackson, Julia S Sigman, Mathieu E Wimmer et al.

Neuropsychopharmacology 2017 43 :1395 - 1404; December 12, 2017; 10.1038/npp.2017.297


Abstract | Full Text

Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway

David M Hedges, J Daniel Obray, Jordan T Yorgason, Eun Young Jang, Vajira K Weerasekara et al.

Neuropsychopharmacology 2017 43 :1405 - 1414; November 29, 2017; 10.1038/npp.2017.291


Abstract | Full Text

Dopamine Receptor-Specific Contributions to the Computation of Value

Christopher J Burke, Alexander Soutschek, Susanna Weber, Anjali Raja Beharelle, Ernst Fehr et al.

Neuropsychopharmacology 2017 43 :1415 - 1424; December 18, 2017; 10.1038/npp.2017.302


Abstract | Full Text

The Protective Action Encoding of Serotonin Transients in the Human Brain

Rosalyn J Moran, Kenneth T Kishida, Terry Lohrenz, Ignacio Saez, Adrian W Laxton et al.

Neuropsychopharmacology 2018 43 :1425 - 1435; January 03, 2018; 10.1038/npp.2017.304


Abstract | Full Text

Neuroactive Steroids and Affective Symptoms in Women Across the Weight Spectrum

Laura E Dichtel, Elizabeth A Lawson, Melanie Schorr, Erinne Meenaghan, Margaret Lederfine Paskal et al.

Neuropsychopharmacology 2017 43 :1436 - 1444; November 01, 2017; 10.1038/npp.2017.269


Abstract | Full Text

Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus

Stefan M Kolata, Kazuhito Nakao, Vivek Jeevakumar, Emily L Farmer-Alroth, Yuko Fujita et al.

Neuropsychopharmacology 2017 43 :1445 - 1456; December 06, 2017; 10.1038/npp.2017.296


Abstract | Full Text

mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex

Elyza Kelly, Samantha M Schaeffer, Sameer C Dhamne, Jonathan O Lipton, Lothar Lindemann et al.

Neuropsychopharmacology 2017 43 :1457 - 1465; December 05, 2017; 10.1038/npp.2017.295


Abstract | Full Text

In Memoriam

John E. Overall

K D Charalampous

Neuropsychopharmacology 2018 43 :1466 - 1466; April 19, 2018; 10.1038/npp.2018.3


Abstract | Full Text

Eddie Way

Charles O'Brien

Neuropsychopharmacology 2018 43 :1467 - 1467; April 19, 2018; 10.1038/npp.2018.4


Abstract | Full Text

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