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Cell Death & Disease

Volume 9 (April 2018)

In this issue
Review Article



Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics

Miriam García Hernández, Ana García Aguilar, Jesús Burillo, Raquel Gómez Oca, Maria Antonietta Manca et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0533-x

Abstract | Full Text

Artemether attenuates LPS-induced inflammatory bone loss by inhibiting osteoclastogenesis and bone resorption via suppression of MAPK signaling pathway

Haobo Wu, Bin Hu, Xiaopeng Zhou, Chenhe Zhou, Jiahong Meng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0540-y

Abstract | Full Text

c-MYC and reactive oxygen species play roles in tetrandrine-induced leukemia differentiation

Guixian Wu, Ting Liu, Han Li, Yafang Li, Dengju Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0498-9

Abstract | Full Text

HOXA4, down-regulated in lung cancer, inhibits the growth, motility and invasion of lung cancer cells

Shaofei Cheng, Fengying Qian, Qin Huang, Lirong Wei, Yawen Fu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0497-x

Abstract | Full Text

Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression

Kezhou Zhu, Wei Liang, Zaijun Ma, Daichao Xu, Shuangyi Cao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0524-y

Abstract | Full Text

DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth muscle cells and disease

Brian G. Jorgensen, Robyn M. Berent, Se Eun Ha, Kazuhide Horiguchi, Kent C. Sasse et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0495-z

Abstract | Full Text

YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD

Mengxue Yu, Yingzhun Chen, Xuelian Li, Rui Yang, Lijia Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0515-z

Abstract | Full Text

The therapeutic effect of miR-125b is enhanced by the prostaglandin endoperoxide synthase 2/cyclooxygenase 2 blockade and hampers ETS1 in the context of the microenvironment of bone metastasis

Paola Maroni, Paola Bendinelli, Emanuela Matteucci & Maria Alfonsina Desiderio

Cell Death & Disease 2018 9: 10.1038/s41419-018-0499-8

Abstract | Full Text

Reduction of Endoplasmic Reticulum Stress Improves Angiogenic Progenitor Cell function in a Mouse Model of Type 1 Diabetes

Maulasri Bhatta, Krishna Chatpar, Zihua Hu, Joshua J. Wang & Sarah X. Zhang

Cell Death & Disease 2018 9: 10.1038/s41419-018-0501-5

Abstract | Full Text

Interaction of the primordial germ cell-specific protein C2EIP with PTCH2 directs differentiation of embryonic stem cells via HH signaling activation

Qisheng Zuo, Kai Jin, Jiuzhou Song, Yani Zhang, Guohong Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0557-2

Abstract | Full Text

Smad proteins differentially regulate obesity-induced glucose and lipid abnormalities and inflammation via class-specific control of AMPK-related kinase MPK38/MELK activity

Hyun-A Seong, Ravi Manoharan & Hyunjung Ha

Cell Death & Disease 2018 9: 10.1038/s41419-018-0489-x

Abstract | Full Text

PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect

Dan Li, Chaoqun Wang, Panfei Ma, Qingan Yu, Mingqi Gu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0494-0

Abstract | Full Text

Class I histone deacetylase (HDAC) inhibitor CI-994 promotes functional recovery following spinal cord injury

Suxiang Zhang, Yuki Fujita, Rieko Matsuzaki & Toshihide Yamashita

Cell Death & Disease 2018 9: 10.1038/s41419-018-0543-8

Abstract | Full Text

ZBTB20 regulates EGFR expression and hepatocyte proliferation in mouse liver regeneration

Hai Zhang, Jian-Hui Shi, Hui Jiang, Kejia Wang, Jun-Yu Lu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0514-0

Abstract | Full Text

FoxM1 drives ADAM17/EGFR activation loop to promote mesenchymal transition in glioblastoma

Chunli Zhang, Xiu Han, Xiao Xu, Zhengrong Zhou, Xi Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0482-4

Abstract | Full Text

Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells

Luc Gailhouste, Lee Chuen Liew, Izuho Hatada, Hitoshi Nakagama & Takahiro Ochiya

Cell Death & Disease 2018 9: 10.1038/s41419-018-0487-z

Abstract | Full Text

LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling

Ailing Li, Rui Peng, Yan Sun, Handeng Liu, Huimin Peng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0527-8

Abstract | Full Text

Mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency increases cisplatin-induced oxidative damage in the kidney tubule cells

Min Jung Kong, Sang Jun Han, Jee In Kim, Jeen-Woo Park & Kwon Moo Park

Cell Death & Disease 2018 9: 10.1038/s41419-018-0537-6

Abstract | Full Text

Helicobacter pylori-induced IL-33 modulates mast cell responses, benefits bacterial growth, and contributes to gastritis

Yi-pin Lv, Yong-sheng Teng, Fang-yuan Mao, Liu-sheng Peng, Jin-yu Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0493-1

Abstract | Full Text

Repression of let-7a cluster prevents adhesion of colorectal cancer cells by enforcing a mesenchymal phenotype in presence of liver inflammation

Lipeng Cheng, Li Geng, Binghua Dai, Tao Zheng, Jun Fu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0477-1

Abstract | Full Text

Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions

Liya Li, Wenjia Liu, Hong Wang, Qianjuan Yang, Liqiang Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0480-6

Abstract | Full Text

BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma

Wondossen Sime, Qiankun Niu, Yasmin Abassi, Katarzyna Chmielarska Masoumi, Reihaneh Zarrizi et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0500-6

Abstract | Full Text

Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis

Shuo Liu, Yun Li, Harry M. C. Choi, Chinmoy Sarkar, Eugene Y. Koh et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0469-1

Abstract | Full Text

The deubiquitinating enzyme UCHL1 negatively regulates the immunosuppressive capacity and survival of multipotent mesenchymal stromal cells

Yuting Gu, Xinyuan Ding, Jiefang Huang, Mingxing Xue, Jie Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0532-y

Abstract | Full Text

Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling

Florian Schubert, Juliane Rapp, Prisca Brauns-Schubert, Lisa Schlicher, Kerstin Stock et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0502-4

Abstract | Full Text

Ube2s stabilizes β-Catenin through K11-linked polyubiquitination to promote mesendoderm specification and colorectal cancer development

Zhaoyan Li, Yan Wang, Yadan Li, Wanqi Yin, Libin Mo et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0451-y

Abstract | Full Text

Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A

Qin He, Shuangyan Yang, Xiuge Gu, Mengying Li, Chunling Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0484-2

Abstract | Full Text

Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation

Xiangyu Dai, Chao Chen, Qianlei Yang, Junchao Xue, Xiong Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0485-1

Abstract | Full Text

REST, regulated by RA through miR-29a and the proteasome pathway, plays a crucial role in RPC proliferation and differentiation

Yuyao Wang, Dandan Zhang, Zhimin Tang, Yi Zhang, Huiqin Gao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0473-5

Abstract | Full Text

Starvation during pregnancy impairs fetal oogenesis and folliculogenesis in offspring in the mouse

Jun-Jie Wang, Xiao-Wei Yu, Rui-Ying Wu, Xiao-Feng Sun, Shun-Feng Cheng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0492-2

Abstract | Full Text

Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis

Pravat Kumar Parida, Barun Mahata, Abhisek Santra, Sohini Chakraborty, Zhumur Ghosh et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0476-2

Abstract | Full Text

Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury

Caixia Wang, Huaiqian Dai, Zhi Xiong, Qiancheng Song, Zhipeng Zou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0483-3

Abstract | Full Text

Seipin deficiency in mice causes loss of dopaminergic neurons via aggregation and phosphorylation of α-synuclein and neuroinflammation

Ling Wang, Juan Hong, Yajuan Wu, George Liu, Wenfeng Yu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0471-7

Abstract | Full Text

A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling

Mara Salomé, Aoife Magee, Krisha Yalla, Shahzya Chaudhury, Evgenia Sarrou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0467-3

Abstract | Full Text

Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

Huilin Ye, Quanbo Zhou, Shangyou Zheng, Guolin Li, Qing Lin et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0486-0

Abstract | Full Text

Inhibition of cyclin-dependent kinase 4 as a potential therapeutic strategy for treatment of synovial sarcoma

Xiaoyang Li, Nicole A. Seebacher, Cassandra Garbutt, Hangzhan Ma, Peng Gao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0474-4

Abstract | Full Text

c-Jun-mediated microRNA-302d-3p induces RPE dedifferentiation by targeting p21Waf1/Cip1

Chao Jiang, Ping Xie, Ruxu Sun, Xiantao Sun, Guohua Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0481-5

Abstract | Full Text

Long non-coding RNA MUC5B-AS1 promotes metastasis through mutually regulating MUC5B expression in lung adenocarcinoma

Shuai Yuan, Qingyun Liu, Zeyao Hu, Zhengyu Zhou, Guilu Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0472-6

Abstract | Full Text

Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo

Eunju Leem, Hyung-Jun Kim, Minji Choi, Sehwan Kim, Yong-Seok Oh et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0491-3

Abstract | Full Text

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Qiang Zhang, Vladimir J. N. Bykov, Klas G. Wiman & Joanna Zawacka-Pankau

Cell Death & Disease 2018 9: 10.1038/s41419-018-0463-7

Abstract | Full Text

Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer

Daniella Brasacchio, Rita A. Busuttil, Tahereh Noori, Ricky W. Johnstone, Alex Boussioutas et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0470-8

Abstract | Full Text

The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells

Karen Legler, Charlotte Hauser, Jan-Hendrik Egberts, Anna Willms, Carola Heneweer et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0478-0

Abstract | Full Text

miR-98-5p contributes to cisplatin resistance in epithelial ovarian cancer by suppressing miR-152 biogenesis via targeting Dicer1

Yanan Wang, Wei Bao, Yuan Liu, Shiyu Wang, Shengjie Xu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0390-7

Abstract | Full Text

Review Article


A dual role for glucocorticoid-induced leucine zipper in glucocorticoid function: tumor growth promotion or suppression?

Emira Ayroldi, Lorenza Cannarile, Domenico V. Delfino & Carlo Riccardi

Cell Death & Disease 2018 9: 10.1038/s41419-018-0558-1

Abstract | Full Text



circRNA disease: a manually curated database of experimentally supported circRNA-disease associations

Zheng Zhao, Kuanyu Wang, Fan Wu, Wen Wang, Kenan Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0503-3

Abstract | Full Text

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