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Molecular Psychiatry

Volume 23, Issue 5 (May 2018)

In this issue
Mechanisms Of Drug Action
Original Articles
Also new


Employed family-based genetic discovery combining linkage analysis and exome sequencing to identify RCL1 as a novel candidate gene for depression, with independent replication in a population-based cohort

N Amin, F M S de Vrij, M Baghdadi, R W W Brouwer, J G J van Rooij et al.

Molecular Psychiatry 2018 23 :1093 - 1093; May 07, 2018; 10.1038/mp.2018.6


Abstract | Full Text

Mechanisms Of Drug Action

Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications

M P Dandekar, A J Fenoy, A F Carvalho, J C Soares & J Quevedo

Molecular Psychiatry 2018 23 :1094 - 1112; February 27, 2018; 10.1038/mp.2018.2


Abstract | Full Text

Original Articles

Elevation of p11 in lateral habenula mediates depression-like behavior

J-S Seo, P Zhong, A Liu, Z Yan & P Greengard

Molecular Psychiatry 2017 23 :1113 - 1119; May 16, 2017; 10.1038/mp.2017.96


Abstract | Full Text

A rare missense variant in RCL1 segregates with depression in extended families

N Amin, F M S de Vrij, M Baghdadi, R W W Brouwer, J G J van Rooij et al.

Molecular Psychiatry 2017 23 :1120 - 1126; March 21, 2017; 10.1038/mp.2017.49


Abstract | Full Text

Vortioxetine reduces BOLD signal during performance of the N-back working memory task: a randomised neuroimaging trial in remitted depressed patients and healthy controls

J Smith, M Browning, S Conen, R Smallman, J Buchbjerg et al.

Molecular Psychiatry 2017 23 :1127 - 1133; May 23, 2017; 10.1038/mp.2017.104


Abstract | Full Text

The microbiome regulates amygdala-dependent fear recall

A E Hoban, R M Stilling, G Moloney, F Shanahan, T G Dinan et al.

Molecular Psychiatry 2017 23 :1134 - 1144; May 16, 2017; 10.1038/mp.2017.100


Abstract | Full Text

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

B P F Rutten, E Vermetten, C H Vinkers, G Ursini, N P Daskalakis et al.

Molecular Psychiatry 2017 23 :1145 - 1156; June 20, 2017; 10.1038/mp.2017.120


Abstract | Full Text

Lateral hypothalamic GLP-1 receptors are critical for the control of food reinforcement, ingestive behavior and body weight

L López-Ferreras, J E Richard, E E Noble, K Eerola, R H Anderberg et al.

Molecular Psychiatry 2017 23 :1157 - 1168; September 12, 2017; 10.1038/mp.2017.187


Abstract | Full Text

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa

L M Huckins, K Hatzikotoulas, L Southam, L M Thornton, J Steinberg et al.

Molecular Psychiatry 2017 23 :1169 - 1180; July 25, 2017; 10.1038/mp.2017.88


Abstract | Full Text

Revealing the complex genetic architecture of obsessive–compulsive disorder using meta-analysis

International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS), Paul D Arnold, Kathleen D Askland, Cristina Barlassina, Laura Bellodi et al.

Molecular Psychiatry 2017 23 :1181 - 1188; August 01, 2017; 10.1038/mp.2017.154


Abstract | Full Text

Perinatal risk factors in Tourette’s and chronic tic disorders: a total population sibling comparison study

G Brander, M Rydell, R Kuja-Halkola, L Fernández de la Cruz, P Lichtenstein et al.

Molecular Psychiatry 2017 23 :1189 - 1197; March 28, 2017; 10.1038/mp.2017.31


Abstract | Full Text

Autism spectrum disorders: a meta-analysis of executive function

E A Demetriou, A Lampit, D S Quintana, S L Naismith, Y J C Song et al.

Molecular Psychiatry 2017 23 :1198 - 1204; April 25, 2017; 10.1038/mp.2017.75


Abstract | Full Text

Autism spectrum disorders and autistic traits share genetics and biology

J Bralten, K J van Hulzen, M B Martens, T E Galesloot, A Arias Vasquez et al.

Molecular Psychiatry 2017 23 :1205 - 1212; May 16, 2017; 10.1038/mp.2017.98


Abstract | Full Text

Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior

M A Hutchison, X Gu, M F Adrover, M R Lee, T S Hnasko et al.

Molecular Psychiatry 2017 23 :1213 - 1225; February 14, 2017; 10.1038/mp.2017.7


Abstract | Full Text

A genome-wide association study for extremely high intelligence

D Zabaneh, E Krapohl, H A Gaspar, C Curtis, S H Lee et al.

Molecular Psychiatry 2017 23 :1226 - 1232; July 04, 2017; 10.1038/mp.2017.121


Abstract | Full Text

Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders

L Yan, A Shamir, M Skirzewski, E Leiva-Salcedo, O B Kwon et al.

Molecular Psychiatry 2017 23 :1233 - 1243; March 21, 2017; 10.1038/mp.2017.22


Abstract | Full Text

CSF GABA is reduced in first-episode psychosis and associates to symptom severity

F Orhan, H Fatouros-Bergman, M Goiny, A Malmqvist, F Piehl et al.

Molecular Psychiatry 2017 23 :1244 - 1250; March 14, 2017; 10.1038/mp.2017.25


Abstract | Full Text

Investigating the neuroimmunogenic architecture of schizophrenia

R Birnbaum, A E Jaffe, Q Chen, J H Shin, BrainSeq Consortium et al.

Molecular Psychiatry 2017 23 :1251 - 1260; May 09, 2017; 10.1038/mp.2017.89


Abstract | Full Text

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

S Kelly, N Jahanshad, A Zalesky, P Kochunov, I Agartz et al.

Molecular Psychiatry 2017 23 :1261 - 1269; October 17, 2017; 10.1038/mp.2017.170


Abstract | Full Text

Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

S Teng, P A Thomson, S McCarthy, M Kramer, S Muller et al.

Molecular Psychiatry 2017 23 :1270 - 1277; June 20, 2017; 10.1038/mp.2017.115


Abstract | Full Text

FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system

K Yalla, C Elliott, J P Day, J Findlay, S Barratt et al.

Molecular Psychiatry 2017 23 :1278 - 1286; July 20, 2017; 10.1038/mp.2017.138


Abstract | Full Text

Cannabis use and risk of schizophrenia: a Mendelian randomization study

J Vaucher, B J Keating, A M Lasserre, W Gan, D M Lyall et al.

Molecular Psychiatry 2017 23 :1287 - 1292; January 24, 2017; 10.1038/mp.2016.252


Abstract | Full Text

Genome-wide association study identifies a novel locus for cannabis dependence

A Agrawal, Y-L Chou, C E Carey, D A A Baranger, B Zhang et al.

Molecular Psychiatry 2017 23 :1293 - 1302; November 07, 2017; 10.1038/mp.2017.200


Abstract | Full Text

EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction

D Mielenz, M Reichel, T Jia, E B Quinlan, T Stöckl et al.

Molecular Psychiatry 2017 23 :1303 - 1319; April 11, 2017; 10.1038/mp.2017.63


Abstract | Full Text

Striatal dopamine D1-type receptor availability: no difference from control but association with cortical thickness in methamphetamine users

K Okita, A M Morales, A C Dean, M C Johnson, V Lu et al.

Molecular Psychiatry 2017 23 :1320 - 1327; September 12, 2017; 10.1038/mp.2017.172


Abstract | Full Text

Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability

M L Miller, Y Ren, H Szutorisz, N A Warren, C Tessereau et al.

Molecular Psychiatry 2017 23 :1328 - 1335; April 25, 2017; 10.1038/mp.2017.80


Abstract | Full Text

A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells

N Gunhanlar, G Shpak, M van der Kroeg, L A Gouty-Colomer, S T Munshi et al.

Molecular Psychiatry 2017 23 :1336 - 1344; April 18, 2017; 10.1038/mp.2017.56


Abstract | Full Text

A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice

D P Ryan, K S Henzel, B L Pearson, M E Siwek, A Papazoglou et al.

Molecular Psychiatry 2017 23 :1345 - 1355; April 04, 2017; 10.1038/mp.2017.53


Abstract | Full Text

Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse

D C Ung, G Iacono, H Méziane, E Blanchard, M-A Papon et al.

Molecular Psychiatry 2017 23 :1356 - 1367; April 18, 2017; 10.1038/mp.2017.39


Abstract | Full Text

Multi-polygenic score approach to trait prediction

E Krapohl, H Patel, S Newhouse, C J Curtis, S von Stumm et al.

Molecular Psychiatry 2017 23 :1368 - 1374; August 08, 2017; 10.1038/mp.2017.163


Abstract | Full Text

Next-gen sequencing identifies non-coding variation disrupting miRNA-binding sites in neurological disorders

P Devanna, X S Chen, J Ho, D Gajewski, S D Smith et al.

Molecular Psychiatry 2017 23 :1375 - 1384; March 14, 2017; 10.1038/mp.2017.30


Abstract | Full Text

Brain age predicts mortality

J H Cole, S J Ritchie, M E Bastin, M C Valdés Hernández, S Muñoz Maniega et al.

Molecular Psychiatry 2017 23 :1385 - 1392; April 25, 2017; 10.1038/mp.2017.62


Abstract | Full Text

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