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Nature Reviews Endocrinology

Query for underlying mechanisms of drug response and progression of diabetes and its complications using Diabetome™.

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August 2018 Volume 14, Issue 8

Research Highlights
News & Views
Consensus Statement
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Research Highlights


Follistatin inactivation improves glucose tolerance    p439
Ivone Leong

Cancer linked to sleep and metabolic disruption    p440
Alan Morris

Redefining metabolically healthy obesity    p440
Claire Greenhill

PRC2 in β-cell function    p441
Ivone Leong

Mechanism underlying beneficial effects of exercise in PCOS identified    p441
Claire Greenhill

Highlights from ECE2018    p441
Ivone Leong

CHRNA2 as a marker for activated beige adipose tissue    p442
Alan Morris

A novel pathway that controls feeding behaviour    p442
Alan Morris

News & Views


Verapamil is a potential therapy for hypoglycaemic brain injury    pp443 - 444
Janice J. Hwang & Robert S. Sherwin

The search for predictive metabolic biomarkers for incident T2DM    pp444 - 446
Ewan Pearson & Jerzy Adamski

Dad’s diet – smRNA methylation signatures in sperm pass on disease risk    pp446 - 447
Rahia Mashoodh & Anne C. Ferguson-Smith

Needle beats pill in gestational diabetes mellitus    pp448 - 449
Alexandra Kautzky-Willer & Jürgen Harreiter

Amino acids — lifesaver or killer in patients with diabetes?    pp449 - 451
Sabine Kahl & Michael Roden



Liver X receptors in lipid signalling and membrane homeostasis    pp452 - 463
Bo Wang & Peter Tontonoz

The liver X receptor (LXR) pathway is important for maintaining cholesterol homeostasis. In this Review, the authors discuss the role of LXRs in cholesterol and lipid metabolism and the emerging strategies to target the LXR pathway to treat metabolic diseases.


Technology in the management of type 1 diabetes mellitus — current status and future prospects    pp464 - 475
Martin Tauschmann & Roman Hovorka

The incidence of type 1 diabetes mellitus (T1DM) is increasing. Novel treatment modalities, particularly from the field of diabetes technologies, have eased the burden of the disease. Here, the authors review established and novel diabetes technologies used in the management of patients with T1DM.


Consensus Statement


Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement    pp476 - 500
Giovanna Mantovani, Murat Bastepe, David Monk, Luisa de Sanctis, Susanne Thiele et al.

This Consensus Statement gives recommendations for the diagnosis and management of patients with pseudohypoparathyroidism and related disorders. A coordinated and multidisciplinary approach from infancy through adulthood is recommended to improve the care of these patients.


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